P2 purinoceptor-activated inward currents in follicular oocytes of Xenopus laevis.
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چکیده
منابع مشابه
Hyperpolarization-activated chloride currents in Xenopus oocytes
During hyperpolarizing pulses, defolliculated Xenopus oocytes have time- and voltage-dependent inward chloride currents. The currents vary greatly in amplitude from batch to batch; activate slowly and, in general, do not decay; have a selectivity sequence of I- > NO3- > Br- > Cl- > propionate > acetate; are insensitive to Ca2+ and pH; are blocked by Ba2+ and some chloride channel blockers; and ...
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Chloride is the most abundant permeable anion in the cell, and numerous studies in the last two decades highlight the great importance and broad physiological role of chloride currents mediated anion transport. They participate in a multiplicity of key processes, as for instance, the regulation of electrical excitability, apoptosis, cell cycle, epithelial secretion and neuronal excitability. In...
متن کاملIon currents of Xenopus laevis oocytes: state of the art.
2. The biology of the oocyte . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214 2.1. Oogenesis and development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214 2.2. Bioelectrical properties of the oocyte . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 2.3. The oocyte at work...
متن کاملTwo bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents.
Ca2+-activated Cl- channels play important diverse roles from fast block to polyspermy to olfactory transduction, but their molecular identity has not been firmly established. By searching sequence databases with the M2 pore domain of ligand-gated anion channels, we identified potential Ca2+-activated Cl- channels, which included members of the bestrophin family. We cloned two bestrophins from ...
متن کاملAntiporter in Xenopus Laevis Oocytes
The amiloride-sensitive Na + /H + antiporter in defolliculated oocytes of Xenopus laevis was characterized by measurements of H Na + influx and apparent H + efflux. Uptake of ^Na"" was linear over a 90-min incubation period and was inhibited approximately 80% with 5xlO~moll~ amiloride. Amiloride-sensitive sodium uptake was reduced following collagenase treatment or oocyte aging. Ko 5 for amilor...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1996
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1996.sp021472